Rabbit Secondary Antibodies
Cayman Chemical ClusTRInCTRm RabbIt Mon 100uL
An ionizable cationic lipid (pKa 6 09) has been used in the generation of LNPs for the delivery of mRNA siRNA and plasmid DNA in vitro and in vivo LNPs containing ALC-0315 and encapsulating siRNA targeting Factor VII mRNA decrease Factor VII mRNA levels in hepatocytes in mice administration of SARS-CoV-2 mRNA in ALC-0315-containing LNPs induces the production of IgG that binds to the SARS-CoV-2 BD) in rhesus macaques with a boost in antigen-specific IgG GMTs seven and 14 days after a second dose LNPs containing ALC-0315 and encapsulating ovalbumin mRNA reduce tumor volume in an ovalbumin-expressing B16/F10 murine melanoma model
Cayman Chemical Np63N-Term RabbIt Monclo 100uL
An mPGES-1 inhibitor (IC50s 117 and 60 nM for the human and mouse enzymes respectively) inhibits LPS-induced PGE2 production in mouse peritoneal cells (IC50 31 nM) reduces carrageenan-induced paw edema in rats at 25 mg/kg
ABclonal Technology 647 Rabbit anti- CD50/ICAM-3
Predicted to enable integrin binding activity Acts upstream of or within phagocytosis Located in plasma membrane Is expressed in brain Orthologous to human ICAM5 (intercellular adhesion molecule 5)
FUJIFILM Biosciences Anti Arg1 Rabbit 100uL
Arginase 1 Arg1 is a hydrolase converting arginine into ornithine and urea expressed highly in M2-type microglia/macrophages This product is a rabbit polyclonal antibody that recognizes Arg1 Useful for visualizing Arg1 in immunocytochemistry studies Specific to Arginase 1 Arg1
American Research Products Inc Rabbit matriX metalloproteinas
Rabbit matriX metalloproteinase 2/Gelatinase A MMP-2 ELISA Kit from CUSABIO Detection Range 1 56 ng/mL-100 ng/mL Sensitivity 0 39 ng/mL Sample serum plasma tissue homogenates Method Sandwich
ABclonal Technology APC Rabbit anti-Mouse CD93 mAb
Predicted to enable complement component C1q complex binding activity Predicted to be involved in cell-cell adhesion Predicted to act upstream of or within cell adhesion Located in cell surface cytoplasmic vesicle and plasma membrane Is expressed in blood vessel Orthologous to human CD93 (CD93 molecule)
ABclonal Technology ABflo 488 Rabbit anti- IgG1
Mouse IgG1 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen It is the most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response Mouse IgG1 is composed of two heavy chains and two light chains and it is involved in opsonization complement activation and antibody-dependent cell-mediated cytotoxicity It is also involved in the regulation of immune responses including the activation of T cells and the inhibition of B cell activation Mouse IgG1 is widely used in research and diagnostic applications including ELISA Western blotting and immunohistochemistry It is also used in therapeutic applications such as immunotherapy and vaccine development
ABclonal Technology ALDH7A1 Rabbit mAb
The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation This particular member has homology to a previously described protein from the green garden pea the 26g pea turgor protein It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix Recent reports show that this protein is found both in the cytosol and the mitochondria and the two forms likely arise from the use of alternative translation initiation sites An additional variant encoding a different isoform has also been found for this gene Mutations in this gene are associated with pyridoxine-dependent epilepsy Several related pseudogenes have also been identified
Cayman Chemical LFA3CD58 RabbIt Monclonal 50uL
An inhibitor of RNA polymerase I-mediated transcription binds to G-quadruplex DNA and inhibits the interaction between ribosomal DNA G-quadruplexes and nucleolin induces nucleolin mislocalization from the nucleoli to the nucleoplasm in A549 cells at 10 UM induces apoptosis in A549 and HL-60 cells at 5 UM reduces tumor growth in MDA-MB-231 and MiaPaCa-2 mouse xenograft models at 5 mg/kg
Cayman Chemical ntIHIstag RabbIt MoncLNa 100ug
Immunogen: Mixture of a peptide with 6xHis-tag at the N-terminus and another peptide with 6xHis-tag at the C-terminus • Host: Rabbit • Species Reactivity: (+) All species • Cross Reactivity: (+) Recombinant proteins containing the 6xHis-tag, 10xHis-tag fused to either the amino or carboxy terminus; (-) Other endogenous protein in mammalian cells or bacteria • Application(s): WB, FC, ICC, IHC, and IP • A probe for immunochemical detection of His tags on recombinant proteins by FC, ICC, IHC, IP, or WB
Cell Signaling Technology PD-L1 D2H6O Rabbit mAb BSA and Azide Free 100 ug
PD-L1 D2H6O Rabbit mAb BSA and Azide Free 100 ug
ABclonal Technology ATP5G1 Rabbit mAb
This gene encodes a subunit of mitochondrial ATP synthase Mitochondrial ATP synthase catalyzes ATP synthesis utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation ATP synthase is composed of two linked multi-subunit complexes the soluble catalytic core F1 and the membrane-spanning component Fo comprising the proton channel The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha beta gamma delta and epsilon) assembled with a stoichiometry of 3 alpha 3 beta and a single representative of the other 3 The proton channel seems to have nine subunits (a b c d e f g F6 and 8) This gene is one of three genes that encode subunit c of the proton channel Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein Alternatively spliced transcript variants encoding the same protein have been identified
ABclonal Technology RPL11 Rabbit mAb
Ribosomes the organelles that catalyze protein synthesis consist of a small 40S subunit and a large 60S subunit Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins This gene encodes a ribosomal protein that is a component of the 60S subunit The protein belongs to the L5P family of ribosomal proteins It is located in the cytoplasm The protein probably associates with the 5S rRNA Alternatively spliced transcript variants encoding different isoforms have been found for this gene As is typical for genes encoding ribosomal proteins there are multiple processed pseudogenes of this gene dispersed through the genome
Cayman Chemical HIston H4CTerm RabbIt Mo 100ug
Immunogen: Peptide corresponding to the C-terminus of human histone H4 • Host: Rabbit • Species Reactivity: (+) Vertebrates • Cross Reactivity: (+) H4A independent of PTMs; (-) Other histone proteins • Applications: ELISA, ICC, multiplex-based assays, WB
ABclonal Technology RAB8A Rabbit mAb
This gene encodes a protein in the RAS superfamily a group of small GTP/GDP-binding proteins ( 200 amino acids) involved in intracellular signaling RAB/YPT family members including this protein may help transport proteins from the endoplasmic reticulum to the Golgi and plasma membrane The protein shares high sequence similarity with dog RAB8 (97%) and mouse MEL (96%) and contains the four conserved GTP/GDP-binding sites typical of RAS proteins It also has a C-terminal CAAX motif common in RAS proteins but absent in most RAB/YPT proteins Although originally identified as a transforming gene from a melanoma cell line no clear link between this gene (MEL) and malignant melanoma has been established It is located about 800 kb downstream of MY09B on chromosome 19p13 1